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ASUS Prime X299-Deluxe II LGA 2066 ATX Motherboard

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$259.05 (US Dollar)
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Product Description

Cool to the Core

Power Delivery Enhancements and Dual ProCool Connectors

With up to 18 cores, four memory channels, and 44 PCIe lanes, the Intel Core processors demand a lot more juice than typical desktop CPUs. The Prime X299-Deluxe II feeds their appetite with 12 power phases hooked up to the socket and two more for the DRAM. It also augments the motherboard's link to the PSU with dual eight-pin connectors that pass 12V of power directly to the processor. These jacks are based on their ProCool design, which uses solid pins that can handle more current than conventional connectors with hollow pins

VRM Design

Higher power requirements are balanced by beefier heatsinks that carefully balance mass and surface area to maximize thermal dissipation. With a VRM-heatsink array and heatpipe positioned in the path of maximum airflow within the chassis, the Prime X299-Deluxe II ensures optimal cooling and system stability for the Intel Core X-series processors.

M.2 Cooling

Two M.2 slots sit under passive heatsinks to ward off the throttling that can occur with sustained transfers. A third pokes out from the PCB vertically near the memory slots, where connected drives benefit from ambient airflow around the CPU socket.

Cooler by Design

The Prime X299-Deluxe II features comprehensive cooling controls that are configurable via FanXpert 4 or the UEFI BIOS:

Multiple Temperature Sources
Each header can dynamically reference three thermal sensors, and via FanXpert 4 you can even map the temperature of supported ASUS graphics cards to optimize cooling for GPU- and CPU-intensive tasks.

Water Pump+
A dedicated header that can supply over 3A to high-performance PWM or DC water pumps.

AIO Pump
A dedicated PWM/DC header for self-contained water-cooling setups.

4-Pin PWM/DC Fan
Every onboard header supports auto-detection of PWM or DC fans.

Bundled Fan Extension Card II
Includes six additional DC or PWM fan headers, plus three thermal-probe headers.

Smart Protection
A dedicated integrated circuit that protects each fan header from over-temperature and over-current.

Fan Extension Card II

The Prime X299-Deluxe II includes ASUS' Fan Extension Card II, which adds six headers that are controllable via FanXpert 4. The card has three temperature-sensor headers to complement the one available onboard, and more importantly, it comes with three thermistors that you can affix to different components. In addition to supplying extra headers for cooling, it has three primed for RGB LED strips.

Screw holes allow you to mount the card to a 2.5" bay on your chassis and the ASUS Node connector allows you to connect an additional compatible PSU or accessories.

Tune It Your Way

5-Way Optimization

One click takes care of all that complex tuning. ASUS 5-Way Optimization makes your PC smart. It dynamically optimizes essential aspects of the system, providing overclocking and cooling profiles that are tailored for your rig.

  • An automated tuning utility that optimizes overclocking and cooling profiles for your unique system configuration.
  • Fans stay whisper-quiet for everyday computing, and deliver optimal airflow when the system is crunching through CPU or GPU-intensive tasks.
  • All-new stress test that allows users to optimize and overclock for CPU or memory-centric workloads.
  • CPU Performance Boost

    The TurboV Processing Unit (TPU) is the intelligence behind ASUS' automated system-tuning utility, offering the ability to fine-tune voltages, monitor system stats, and adjust overclock parameters for improved performance.

    All-Round Energy Efficiency

    With the Energy Processing Unit (EPU), you'll enjoy system-wide power savings. The EPU automatically optimizes power consumption and maximizes savings with Away Mode, a smart setting that creates an extreme energy-saving scenario by shutting down unused I/O controllers.

    Flexible Cooling Controls for Air or Liquid

    With the Prime X299-Deluxe II, you have comprehensive controls over fans via FanXpert 4 or their UEFI BIOS. Whether you're cooling with air or water, Auto Tuning Mode intelligently configures all parameters with a single click. There's also an Extreme Quiet Mode, which reduces all fan speeds to below the default minimum, which helps keep your system even quieter when performing light tasks.

    Digi+ Power Control

    Digi+ delivers real-time control over voltage droop, switching frequency and power efficiency settings, allowing you to fine tune CPU voltage regulation for greater stability and performance.

    Turbo Core App

    Intel processors feature per-core tuning, and the ASUS Turbo Core app makes use of this feature by enabling you to assign applications to specific processor cores, allowing you to prioritize computer power where it's needed most.


    The UEFI BIOS is an early waypoint on any PC-building journey, and Prime X299-Deluxe II offers one of the best in the business.

    EZ Mode

    EZ Tuning Wizard
    Quickly apply a CPU overclock to improve system performance or configure a RAID array for faster data retrieval and backups.

    Graphical Fan Control
    Fine-tune individual fans by dragging a curve with the mouse.

    EZ XMP
    Improve your DRAM performance with a click.

    SATA Information
    Display SATA port details for device identification.

    Fast Clock Adjustment
    Use mouse controls to change the time and date settings.

    Advanced Mode

    Aura On/Off Mode
    Enable or disable Aura RGB lighting or every onboard LED, for a more subdued aesthetic.

    Search Function
    Quickly and easily find the option or setting you're looking for.

    ASUS BIOS Profile
    Save BIOS settings for migration to a new BIOS version or system.

    GPU Post
    View recommendations for multi-VGA configurations and detailed information for selected ASUS graphics cards.

    My Favorites
    Quickly discover tuning options and add preferred tools to the list.

    OC Design - ASUS PRO Clock II Technology

    The Prime X299-Deluxe II includes a dedicated base-clock (BCLK) generator that extends CPU and memory overclocking margins. This custom solution works in tandem with the TPU to enhance voltage and BCLK overclocking control, providing the flexibility to extract every ounce of performance from the Intel Core X-series processors.

    Make Your Memory Go Faster

    With optimized trace paths for time-aligned signaling and minimal crosstalk, third-generation ASUS T-Topology offers enhanced memory stability and compatibility, allowing support for DDR4 memory speeds of 4266 MHz and beyond.

    Load Up with Graphics and Storage

    Multi-GPU Support

    Fully loaded takes on new meaning when you have up to 44 PCI Express lanes stemming from the CPU. Those lanes can be split in a x16/x16/x8 configuration spanning the board's trio of PCIe x16 slots, allowing you to load up on GPUs to accelerate an increasingly diverse array of workloads that include 3D rendering, scientific research, financial modeling, and AI training.


    SafeSlot is the PCIe slot reinvented by ASUS and engineered to provide improved retention and shearing resistance. Manufactured in a single step using an insert molding process, SafeSlot integrates the slot with fortifying metal for an inherently stronger slot, which is then firmly anchored to the PCB through additional solder points.

    VROC - Upgrade your RAID

    The PCIe slots can be used to connect bootable RAID arrays directly to the CPU via Intel's VROC technology and a special key that plugs into the motherboard. With their Hyper M.2 x16 Card V2 installed, the Prime X299-Deluxe II is able to host up to four NVMe SSDs on a single x16 card with integrated cooling. Factor in the ability to add an onboard SSD and that's access to a lot of ultra-fast storage, plus VROC supports arrays that span multiple cards for even higher speeds and capacities.


    With PCI Express 3.0/2.0 x4 bandwidth, M.2 supports data transfer speeds of up to 32 Gb/s. It's a good choice for an operating system or application drive, providing fast access to data. And all three slots support longer 110mm M.2 drives with more room for flash storage than shorter 80mm sticks.

    Intel Optane Memory

    Intel Optane is a non-volatile memory technology supported by the Prime X299-Deluxe II. Intel Optane memory modules accelerate attached storage to reduce boot and load times, so everything feels faster and more responsive.

    Fast Connectivity

    Thunderbolt 3 Port

    High-speed external storage is required for many workstations, so the Prime X299-Deluxe II integrates Thunderbolt 3 with up to 40 Gb/s of aggregate interface bandwidth. The rear I/O panel has dual Thunderbolt 3 (USB Type-C) ports that support data in addition to DisplayPort 1.4 output. Up to six devices can be daisy-chained from one Thunderbolt 3 port, with the provision of up to 15W of power for fast-charging devices connected in this way.

    USB 3.1 Gen 2 Front-Panel Connector

    The Prime X299-Deluxe II's front panel USB 3.1 connector is ready for next-gen PC cases and devices.

    Intel Wireless-AC 9260

    The Prime X299-Deluxe II features Intel Wireless AC-9260 Wi-Fi 5 (802.11ac) with 2x2 MU-MIMO and wide 160 MHz channels, for wireless speeds of up to 1.73 Gb/s. In fact, its integrated Wireless-AC 9260 Wi-Fi adapter pushes wireless data up to 2X faster than other Wi-Fi solutions, so you'll get fast, smooth transfers, even when your rig is farther away from the router. Intel Wireless-AC 9260 also offers Bluetooth 5.0 for connections that are up to 2X faster and with up to 4X the range.

    Aquantia AQC-111C 5G LAN

    The Prime X299-Deluxe II has 5 Gb/s Ethernet onboard to deliver up to 5X the bandwidth of standard Gigabit Ethernet. You'll enjoy streaming uncompressed 4K UHD videos without stutter, and backups and file transfers that are faster. There's also support for intermediate connections, so it's easy to choose your ideal bandwidth and benefit from low latency at speeds up to 5 Gb/s.

    Intel Ethernet

    The Prime X299-Deluxe II features Intel Gigabit Ethernet. Intel's LAN has the advantage of reducing CPU overhead and offering high TCP and UDP throughput for faster, smoother data transfers.


    ASUS LANGuard is hardware-level networking protection that employs signal-coupling technology and premium anti-EMI surface-mounted capacitors to help ensure a more reliable connection and better throughput.

    Turbo LAN

    Turbo LAN with cFosSpeed traffic-shaping technology allows you to configure application priority via an intuitive interface and reduces network lag.

    Upgrade Your Audio

    Outstanding Audio

    The Prime X299-Deluxe II utilizes a unique audio codec designed in close collaboration with Realtek - the Realtek S1220A. It also features a 120-dB signal-to-noise ratio for the stereo line-out and a 113-dB SNR for the line-in, providing pristine audio quality. Additionally, an impedance-sensing circuit automatically adjusts gain to ensure a proper volume range for your headphones.

    DTS Headphone:X

    Immersive 3D surround-sound technology provides an improved audio experience.

    Crystal Sound 3

    Power Pre-Regulator
    Reduces power-input noise to ensure consistent performance.

    Audio Shielding
    Separates analog/digital signal domains, significantly reducing multi-lateral interference.

    Separate Layer for Left and Right Tracks
    Ensures minimal crosstalk between audio paths.

    Integrated Amplifier
    Capable of driving high-impedance headphones, without rolling-off high or low frequencies.

    De-Pop Circuit
    Reduces start-up popping noise to all audio outputs.

    Japanese Audio Capacitors
    Premium parts provide an immersive sound signature with high fidelity.

    User-Friendly Extras

    Pre-Mounted I/O

    Form meets function in the pre-mounted I/O shield ASUS pioneered with the ROG series. Now available on the Prime X299-Deluxe II, this feature streamlines the installation process for budding builders and savvy enthusiasts alike.

    LiveDash OLED

    The Prime X299-Deluxe II has a 2" LiveDash OLED dominating the center of the board. It's positioned for easy visibility and capable of showing vital system stats like clock speeds, temperatures, and voltages. For a more personalized touch, it's easy to add text and custom images, including animated GIFs.

    ASUS Node

    The ASUS Node connector offers a bidirectional interface with lots of potential for DIY components and builds. The included ASUS Fan Extension Card II connects via Node, while In Win is developing a compatible OLED panel that fits into a chassis and offers both LiveDash functionality and the ability to boot directly to the UEFI. FSP has also created the HydroDPM 1000W PSU that connects to Node to share power stats, temperatures, and enable control over the CPU fan.

    Aura Sync

    A well-tuned enthusiast system deserves a matching aesthetic. ASUS Aura offers full RGB lighting control with a variety of functional presets for the built-in RGB LEDs, as well as the LED strips connected to the onboard 4-pin RGB headers. It can all be synced with an ever-growing portfolio of Aura-capable ASUS hardware.

    Addressable RGB LED Strip Header

    The Prime X299-Deluxe II now has a dedicated addressable RGB header, suitable for connecting to lighting strips, fans, and compatible PC cases. ASUS' Aura software contains an array of effects for addressable gear, and the Aura SDK takes things to the next level, allowing developers to control each LED individually - unleashing infinite lighting possibilities.

    ASUS Q-Installer

    Q-Installer software lets you download all of the latest drivers and utilities for your board with a single click, or select only the ones you want.


    Intel X299 Chipset

    The Intel X299 chipset supports LGA 2066 socket Intel Core X-series processors. It provides improved performance by utilizing serial point-to-point links, allowing increased bandwidth and stability. Additionally, X299 provides a maximum of 10 USB 3.1 Gen 1 ports, 8 SATA III 6 Gb/s ports, and 32 Gb/s M.2 support for faster data retrieval.

    Intel Core X-Series Processors for LGA 2066 Socket

    Intel Core X-series processors (6-core and above): 4-channel (8-DIMM), 44/28 PCI Express 3.0/2.0 lanes.

    Product Specification




    Chipset Intel X299
    CPU Socket LGA 2066 (R4)


    Back Panel I/O


    USB 4 x USB 3.1 / USB 3.2 Gen 1 Type-A
    2 x USB 2.0 Type-A
    Thunderbolt 2 x Thunderbolt 3
    Display 2 x DisplayPort 1.4
    Audio 5 x 3.5 mm
    1 x S/PDIF
    Ethernet / Controller 1 x Aquantia AQC-111C 5G LAN
    1 x Intel I219V Gigabit
    Wi-Fi Antenna 2 x Connector
    Buttons BIOS Flashback




    Memory Slots 8 x 288-Pin
    Memory Support DDR4 2133, 2400, 2666, 3600, 4000, 4133, 4200, 4266 MHz
    Maximum Capacity 128 GB
    Channel Architecture Quad Channel
    ECC Support Non-ECC Unbuffered


    Storage Expansion


    M.2 2 x M Key 2242, 2260, 2280, 22110 (PCIe 3.0 x4)
    1 x M Key 2242, 2260, 2280, 22110 (PCIe 3.0 x4, SATA III)
    U.2 None
    Optane Memory Support Yes
    RAID Support RAID 0, 1, 5, 10


    Internal I/O


    Expansion Slots 3 x PCIe 3.0 x16
    2 x PCIe 3.0 x1
    USB 2 x USB 3.1 / USB 3.2 Gen 1 Header (Supports 4 USB Type-A Port)
    1 x USB 2.0 Header (Supports 2 USB Type-A Port)
    Multi-GPU Support 2-Way, 3-Way, Quad-GPU NVIDIA SLI
    3-Way, Quad-GPU AMD CrossFireX
    Air Cooling 1 x 4-Pin M.2
    1 x 4-Pin CPU
    1 x 4-Pin Assistant
    2 x 4-Pin System
    Liquid Cooling 2 x 4-Pin Pump
    Power Connectors 1 x 24-Pin Mainboard
    2 x 8-Pin CPU
    Security Chassis Intrusion
    LED Header 1 x RGB
    Diagnostics Clear CMOS, CPU Overclock, EZ XMP, Power, RAM Check, Reset




    ROM 128 Mb


    Front Panel I/O


    I/O Connection Headers AAFP, USB 3.1 / USB 3.2 Gen 1




    Audio Codec Realtek S1220A (8-Channel)




    Bluetooth 5.0
    Wi-Fi Wi-Fi 5 (802.11ac)




    Supported Operating Systems Windows 10




    Form Factor ATX
    Dimensions 12.0 x 9.6" / 30.5 x 24.4 cm


    Packaging Info


    Package Weight 6.165 lb
    Box Dimensions (LxWxH) 14.6 x 12.3 x 4.45"



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